Research Projects

RNA-mediated gene regulation: • Discovery of transcriptional active RNAs • Genome-wide investigation of RNA binding protein cooperation and competition • Discovery and characterization of functional long non-coding RNAs in diseases • Explorations of evolution and adaptive regulation by testis-specific hairpin RNA-target interaction networks across insect genomes • Roles for RNA binding proteins in regulating alternative polyadenylation (APA) in the central nervous system • Roles for alternative polyadenylation (APA) in the heart (in collaboration with Prof. Thomas Preiss’s group at JCSMR, ANU)

Transcriptional regulation – in collaboration with Dr. Qi Dai’s Group at Stockholm University, Sweden • Gene regulation by cell-type specific transcription factor networks controlling neural cell fate specification • Neural cell-specific transcription factor networks regulate neural stem cell self-renewal and differentiation

Epigenetics regulation – in collaboration with Prof. Mattias Mannervik’s Group at Stockholm University, Sweden • Investigation of the function of histone acetylation • Transcriptional coregulators modifying chromatin structures.

Single cell analysis in immunity – in collaboration with A/Prof Di Yu’s Group at JCSMR, ANU